●Menene Berberine?
Berberine alkaloids ne na halitta wanda aka samo daga tushen, mai tushe da haushi na tsire-tsire iri-iri, kamar Coptis chinensis, Phellodendron amurense da Berberis vulgaris. Shi ne babban sashi mai aiki na Coptis chinensis don maganin kashe kwayoyin cuta.
Berberine crystal ne mai launin rawaya mai siffar allura mai ɗanɗano mai ɗaci. Babban abu mai ɗaci a cikin Coptis chinensis shine berberine hydrochloride. Wannan shine isoquinoline alkaloid wanda aka rarraba a cikin ganyayyaki na halitta daban-daban. Ya wanzu a Coptis chinensis a cikin hanyar hydrochloride (berberine hydrochloride). Nazarin ya gano cewa ana iya amfani da wannan fili don magance ciwace-ciwacen daji, cututtukan hanta, cututtukan zuciya, hauhawar jini, kumburi, cututtukan ƙwayoyin cuta da ƙwayoyin cuta, gudawa, cutar Alzheimer da arthritis.
Menene Amfanin Berberine Lafiya?
1.Antioxidant
A karkashin yanayi na al'ada, jikin mutum yana kula da daidaituwa tsakanin antioxidants da prooxidants. Danniya na Oxidative wani tsari ne mai cutarwa wanda zai iya zama mahimmancin matsakanci na lalacewar tsarin salula, ta haka ya haifar da cututtuka daban-daban kamar cututtukan zuciya, ciwon daji, cututtuka na jijiyoyin jini da ciwon sukari. Yawan samar da nau'in iskar oxygen mai amsawa (ROS), galibi ta hanyar wuce gona da iri na NADPH ta cytokines ko ta hanyar sarkar jigilar lantarki ta mitochondrial da xanthine oxidase, na iya haifar da damuwa. Gwaje-gwaje sun nuna cewa berberine metabolites da berberine suna nuna kyakkyawan aiki -OH scavenging aiki, wanda yake daidai daidai da bitamin C mai ƙarfi antioxidant. alamar lipid peroxidation) matakan [1]. Ƙarin sakamako ya nuna cewa aikin ɓarna na berberine yana da alaƙa da alaƙa da aikin ferrous ion chelating, kuma ƙungiyar C-9 hydroxyl na berberine wani muhimmin sashi ne.
2.Anti-tumor
An sami rahotanni da yawa game da tasirin maganin cutar kansaberberine. Nazarin daban-daban a cikin 'yan shekarun nan sun nuna cewa berberine yana da matukar muhimmanci wajen maganin cututtukan daji masu tsanani kamar ciwon daji na ovarian, ciwon daji na endometrial, ciwon mahaifa, ciwon nono, ciwon huhu, ciwon daji, ciwon koda, ciwon mafitsara, da ciwon prostate. [2]. Berberine na iya hana yaduwar ƙwayoyin tumor ta hanyar yin hulɗa tare da maƙasudai da hanyoyi daban-daban. Zai iya canza maganganun oncogenes da kwayoyin da ke da alaka da carcinogenesis don cimma manufar daidaita ayyukan enzymes masu dangantaka don hana haɓakawa.
3.Rage Lipids na Jini Da Kare Tsarin Zuciya
Berberine yana taka muhimmiyar rawa wajen magance cututtuka na zuciya da jijiyoyin jini kuma yana da aikace-aikace iri-iri. Berberine yana cimma manufar anti-arrhythmia ta hanyar rage yawan bugun bugun zuciya da kuma hana faruwar tachycardia na ventricular. Abu na biyu, dyslipidemia babban haɗari ne ga cututtukan zuciya da jijiyoyin jini, wanda ke da alaƙa da haɓakar matakan jimlar cholesterol, triglycerides, da ƙarancin ƙarancin lipoprotein cholesterol (LDL), da raguwar matakan lipoprotein mai girma (HDL), kuma berberine na iya kiyayewa sosai. kwanciyar hankali na waɗannan alamomi. Hyperlipidemia na dogon lokaci shine muhimmin dalilin samuwar atherosclerotic plaque. An ba da rahoton cewa berberine yana rinjayar masu karɓar LDL a cikin hepatocytes don rage matakan cholesterol na jikin mutum a cikin hanta. Ba wai kawai ba,berberineyana da sakamako mai kyau na inotropic kuma an yi amfani dashi don magance cututtukan zuciya.
4. Yana Rage Sigar Jini Kuma Yana Kayyade Endocrine
Ciwon sukari mellitus (DM) cuta ce ta rayuwa wacce ke da haɓakar matakan sukari na jini (hyperglycemia) wanda ya haifar da gazawar ƙwayoyin pancreatic B don samar da isasshen insulin, ko asarar ingantaccen martanin nama ga insulin. An gano tasirin hypoglycemic na berberine bisa kuskure a cikin 1980s a cikin kula da masu ciwon sukari tare da gudawa.
Yawancin bincike sun nuna hakanberberineyana rage sukarin jini ta hanyoyi masu zuwa:
● Yana hana mitochondrial glucose oxidation kuma yana ƙarfafa glycolysis, sa'an nan kuma ƙara yawan glucose metabolism;
● Rage matakan ATP ta hanyar hana aikin mitochondrial a cikin hanta;
● Yana hana ayyukan DPP 4 (wani nau'in protease na serine a ko'ina), ta haka yana raba wasu peptides waɗanda ke aiki don ƙara matakan insulin a gaban hyperglycemia.
● Berberine yana da tasiri mai tasiri akan inganta juriya na insulin da amfani da glucose a cikin kyallen takarda ta hanyar rage lipids (musamman triglycerides) da matakan fatty acid kyauta na plasma.
Takaitawa
A halin yanzu,berberineana iya haɗa su ta hanyar wucin gadi kuma an gyara su ta hanyoyin injiniyan crystal. Yana da ƙananan farashi da fasaha na ci gaba. Tare da haɓaka binciken likitanci da zurfafa bincike na sinadarai, tabbas berberine zai nuna ƙarin tasirin magani. A gefe guda, berberine ba kawai ya sami sakamako mai ban mamaki ba a cikin binciken magungunan gargajiya na gargajiya a cikin maganin ƙwayoyin cuta, antiviral, anti-inflammatory, anti-tumor, anti-diabetic, da kuma kula da cututtuka na zuciya da jijiyoyin jini da kuma cututtuka na cerebrovascular, amma har ma zane-zanen injiniya na crystal da nazarin halittu. sun sami kulawa sosai. Saboda tasirinsa mai mahimmanci da ƙananan mai guba da sakamako masu illa, yana da babban tasiri a aikace-aikacen asibiti kuma yana da fa'ida. Tare da haɓaka ilimin ilimin halitta, tsarin ilimin likitanci na berberine za a fayyace daga matakin salon salula har ma da matakan ƙwayoyin cuta da maƙasudi, yana ba da ƙarin tushen ka'idoji don aikace-aikacen asibiti.
● SABON KYAUTABerberine/Liposomal Berberine Foda/Capsules/Allunan
Lokacin aikawa: Oktoba-28-2024