Yayin da muke tsufa, aikin sassan jikin mutum yana raguwa a hankali, wanda ke da alaƙa da haɓakar cututtuka na neurodegenerative. An yi la'akari da rashin aikin mitochondrial a matsayin ɗaya daga cikin mahimman abubuwan da ke cikin wannan tsari. Kwanan nan, tawagar binciken Ajay Kumar daga Cibiyar Hadin Kan Sinanci da Magungunan Yammacin Yamma ta Indiya ta buga wani muhimmin sakamakon bincike a cikin ACS Pharmacology & Kimiyyar Fassara, wanda ya bayyana hanyar da ta biyo baya.crocetinyana jinkirta tsufa na kwakwalwa da jiki ta hanyar inganta matakan makamashin salula.
Mitochondria sune "masana'antar makamashi" a cikin sel, alhakin samar da mafi yawan makamashin da sel ke buƙata. Tare da shekaru, raguwar aikin huhu, anemia, da rashin lafiya na microcirculatory suna haifar da rashin isashshen iskar oxygen zuwa kyallen takarda, haifar da hypoxia na yau da kullun da tabarbarewar mitochondrial, ta haka yana haɓaka ci gaban cututtukan neurodegenerative. Crocetin wani fili ne na halitta tare da yuwuwar inganta aikin mitochondrial. Wannan binciken yana nufin gano tasirin crocetin akan aikin mitochondrial a cikin tsofaffin beraye da tasirin sa na tsufa.
● MeneneCrocetin?
Crocetin shine dicarboxylic acid apocarotenoid na halitta wanda aka samo a cikin furen crocus tare da glycoside, crocetin, da 'ya'yan itatuwa jasminoides Gardenia. Ana kuma san shi da crocetic acid.[3][4] Yana samar da bulo ja lu'ulu'u tare da wurin narkewa na 285 ° C.
Tsarin sinadarai na crocetin ya zama tsakiyar tsakiya na crocetin, fili da ke da alhakin launi na saffron. Crocetin yawanci ana hakowa ta kasuwanci ne daga 'ya'yan itacen lambu, saboda tsadar saffron.
●Yaya YayiCrocetinHaɓaka Makamashin Salon salula ?
Masu binciken sun yi amfani da mice masu shekaru C57BL/6J. An raba tsoffin berayen zuwa rukuni biyu, rukuni ɗaya ya karɓi maganin crocetin na tsawon watanni huɗu, ɗayan rukunin kuma ya zama ƙungiyar kulawa. An kimanta fahimi da ƙarfin motsa jiki na beraye ta hanyar gwaje-gwajen ɗabi'a kamar gwajin ƙwaƙwalwar sararin samaniya da gwaje-gwajen filin buɗe ido, kuma an bincika tsarin aikin crocetin ta hanyar nazarin pharmacokinetic da cikakken jerin bayanan rubutu. An yi amfani da bincike mai yawa na regression don daidaitawa don abubuwa masu banƙyama kamar shekaru da jinsi don kimanta tasirin crocetin akan fahimi da ayyukan motsa jiki na mice.
Sakamakon ya nuna cewa bayan watanni hudu nacrocetinjiyya, halayen ƙwaƙwalwar ajiya da ikon motsi na mice sun inganta sosai. Ƙungiyar jiyya ta yi mafi kyau a cikin gwajin ƙwaƙwalwar ajiyar sararin samaniya, sun ɗauki ɗan lokaci don nemo abinci, sun daɗe a cikin hannun da ba a daɗe ba, kuma sun rage yawan lokutan da suka shiga hannun da ba a kai ba bisa kuskure. A cikin gwajin filin buɗe ido, berayen da ke cikin rukunin da aka yi wa crocetin sun fi aiki, kuma sun ƙaru da nisa da sauri.
Ta hanyar jera dukkan rubutun hippocampus na linzamin kwamfuta, masu binciken sun gano hakancrocetinjiyya ya haifar da canje-canje masu mahimmanci a cikin maganganun kwayoyin halitta, ciki har da haɓakar maganganun kwayoyin halitta irin su BDNF (factor neurotrophic da aka samu na kwakwalwa).
Nazarin Pharmacokinetic ya nuna cewa crocetin yana da ƙananan ƙididdiga a cikin kwakwalwa kuma ba shi da tarawa, yana nuna cewa yana da lafiya. crocetin ya inganta ingantaccen aikin mitochondrial da haɓaka matakan makamashi na salula a cikin tsofaffin beraye ta hanyar haɓaka yaduwar iskar oxygen. Ingantacciyar aikin mitochondrial yana taimakawa rage tsarin tsufa na kwakwalwa da jiki da tsawaita tsawon rayuwar beraye.
Wannan binciken ya nuna cewacrocetinna iya jinkirin jinkirin ƙwaƙwalwa da tsufa na jiki da tsawaita rayuwa a cikin tsofaffin beraye ta hanyar haɓaka aikin mitochondrial da haɓaka matakan makamashi na salula. Takamaiman shawarwari sune kamar haka:
Ƙarin crocetin a cikin matsakaici: Ga tsofaffi, haɓaka crocetin a matsakaici na iya taimakawa wajen inganta haɓakar fahimi da motsa jiki da jinkirta tsarin tsufa.
Cikakken kula da lafiya: Baya ga kari na crocetin, ya kamata ku kula da abinci mai kyau, motsa jiki na yau da kullun da ingantaccen ingancin bacci don haɓaka lafiyar gabaɗaya.
Kula da aminci: Ko da yakecrocetinyana nuna aminci mai kyau, har yanzu kuna buƙatar kula da adadin lokacin da kuke ƙarawa kuma kuyi shi ƙarƙashin jagorancin likita ko masanin abinci mai gina jiki.
●NEWGREEN Supply Crocetin /Crocin / Saffron Cire
Lokacin aikawa: Oktoba-23-2024
